الأحد، 22 ديسمبر 2013

VELscope.. A new Technology to detect oral cancer and other oral lesions

VELscope.. A new Technology to detect oral cancer and other oral lesions

The VELscope is a hand-held device that provides dentists and hygienists with an easy-to-integrate adjunctive mucosal examination system for the early detection of a wide variety of oral diseases, including pre-cancer and cancer. Used in conjunction with the conventional intra-oral and extra-oral head and neck exam, the VELscope facilitates the discovery of mucosal abnormalities before they become visible under ordinary light. The VELscope is the only non-invasive adjunctive device clinically proven to help discover occult oral disease according to the device developers.
Many clinical trials has studied Velscope efficiency, Huber 2009 has raised a question in his research concerning the utilization of the VELscope as a screening adjunct as he found that VELscope interpretation did not enhance or otherwise alter the clinical management of the suspicious lesions.
While Hanken et al., 2013 has cocluded in their clinical trial that The VELscope device is a simple, non-invasive test of the oral mucosa, which can help the experienced clinician to find oral precursor malignant lesions and the correct location for taking biopsies within the altered mucosa. Nevertheless, the results should be interpreted with caution due to the issue of frequently occurring false positive results. The device should not be used in the hands of unexperienced clinicians and cannot be a replacement for the gold standard of any histological evaluation. At the moment the device can only be recommended to exclude any suspicious lesion.
According to the device developers like other visualization technologies, such as panoramic radiography, CT, MRI, PET and ultrasound, the VELscope is NOT a stand-alone diagnostic test. However, used in conjunction with the standard oral soft tissue exam, VELscope provides visual information that cannot be acquired in any other way. And that The VELscope system is NOT a diagnostic test, and does not, consequently, generate false positives. As an adjunctive visualization tool, the VELscope helps dental professionals discover a wide range of unhealthy tissue in the mouth, including oral pre-cancer and cancer.
A recent 620-patient study at the University of Washington has provided additional insights into VELscope's potential. Within a dental school setting, the addition of VELscope to routine clinical examinations resulted in the detection of a number of mucosal abnormalities not detected by the conventional exam. Importantly, these abnormalities included not only a number of dysplasias, but also lichen planus and other inflammatory lesions. 

The study highlights an aspect of VELscope that is sometimes overlooked. In addition to the detection of oral cancers and pre-cancers, the VELscope system is showing itself to be a powerful tool for the discovery of mucosal abnormalities such as: Viral, fungal and bacterial infections, Inflammation from a variety of causes (including lichen planus and other lichenoid reactions), Squamous papillomas ,Salivary gland tumours.

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